← Back to codex

Cortagen

Aliases: Ala-Glu-Asp-Pro · AEDP

Last verified: 2026-09-23

Research chemicalLimited evidenceBioregulatorsLow interest

The short version

A brain-series tetrapeptide — neuroprotection and nerve-tissue regeneration; potential in TBI and neurodegeneration. Key fact: Human data are limited: small trials or case-series reports exist, without large randomized studies. Preclinical studies. Status: research chemical. Not approved in the West.

Identity & type

Molecular type
bioregulator
Origin
A brain-series tetrapeptide — neuroprotection and nerve-tissue regeneration; potential in TBI and neurodegeneration.

Mechanism of action

Regulation of neuronal-differentiation gene expression; reduced oxidative stress.

not confirmed in humans

Dosing & routes

Official / clinical context

No approved official document exists for Cortagen. Any protocols mentioned are to be read as information, not as a recommendation.

Regulator-approved labeling and published study designs — never a recommendation.

Community-reported practice

1–5 mg/day SC in courses. A brain bioregulator: users describe a mild calming/clarity effect; often combined with Pinealon.

Unverified self-reports. Not medical advice. Not endorsement.

Expected effects (community)

A brain bioregulator: users describe a mild calming/clarity effect; often combined with Pinealon.

Protocol — official vs community

Official / label

No approved protocol exists. Cortagen is a research peptide bioregulator (Ala-Glu-Asp-Pro) with no registered drug product in any major market.

Duration:

Preclinical neuroprotection data from the originating group; no registered human trial.

Community (anecdotal)

1–5 mg SC daily for 10–20 days.

Cycle:
1–2 courses per year.
Break:
Months between courses.

The regimen is the shared Khavinson course pattern; only the brain/neuroregeneration targeting claim differs from the rest of the series.

Human evidence

Human data are limited: small trials or case-series reports exist, without large randomized studies. Preclinical studies.

Preclinical evidence

Preclinical studies.

Known risks

  • None reported.characterized
  • Unregulated injectable supply — sterility, purity and accurate dose not assuredtheoretical

Teal: characterized in clinical/labeling contexts. Amber: theoretical or reported outside controlled settings.

Unknowns & evidence gaps

  • Long-term human safety
  • Optimal dose and pharmacokinetics

Frequently asked questions

References

Systematic references are being expanded; verify sources directly before any decision.