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LGD-3303

Aliases: LGD3303

Last verified: 2026-09-23

PreclinicalPreclinical evidenceSARMsLow interest

The short version

A SARM focused on bone/muscle with very low androgenic effects; never entered serious clinical development, but present on the gray market. Key fact: No controlled human trials exist. Everything known about LGD-3303 in humans comes from indirect sources and self-reports. Status: preclinical. Not approved; WADA-banned (S1).

Identity & type

Molecular type
SARM
Origin
A SARM focused on bone/muscle with very low androgenic effects; never entered serious clinical development, but present on the gray market.

Mechanism of action

Selective AR agonism.

not confirmed in humans

Dosing & routes

Official / clinical context

No approved official document exists for LGD-3303. Any protocols mentioned are to be read as information, not as a recommendation.

Regulator-approved labeling and published study designs — never a recommendation.

Community-reported practice

Community: 10–20 mg/day. Dryness and strength without much water; rare experiences, the community treats it as a "specialized" SARM.

Unverified self-reports. Not medical advice. Not endorsement.

Expected effects (community)

Dryness and strength without much water; rare experiences, the community treats it as a "specialized" SARM.

Protocol — official vs community

Official / label

No official protocol exists — this compound has no approved product.

Community (anecdotal)

10–20 mg oral daily.

Cycle:
6–8 weeks.
Break:
4+ weeks with SERM-based PCT.

Positioned as a 'dry' LGD — strength and hardness without the water retention associated with LGD-4033. Experiences are rare and the compound is treated as a specialized, second-tier option.

Human evidence

No controlled human trials exist. Everything known about LGD-3303 in humans comes from indirect sources and self-reports.

Preclinical evidence

Preclinical (Ligand Pharmaceuticals).

Known risks

  • Unknown in humans; suppression likely.characterized
  • WADA prohibition (S1 anabolic agents)characterized

Teal: characterized in clinical/labeling contexts. Amber: theoretical or reported outside controlled settings.

Unknowns & evidence gaps

  • All human pharmacokinetics, safety and efficacy

Frequently asked questions

References

Systematic references are being expanded; verify sources directly before any decision.