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PF-06260414

Aliases: PF06260414

Last verified: 2026-09-23

DiscontinuedLimited evidenceSARMsLow interest

The short version

A Pfizer SARM for cachexia/sarcopenia — Phase I completed, development discontinued. Key fact: Human data are limited: small trials or case-series reports exist, without large randomized studies. Phase I completed; no further development. Status: discontinued. Not approved; WADA-banned (S1).

Identity & type

Molecular type
SARM
Origin
A Pfizer SARM for cachexia/sarcopenia — Phase I completed, development discontinued.

Mechanism of action

Selective AR agonism.

not confirmed in humans

Dosing & routes

Official / clinical context

Development was abandoned; no active regulatory document exists. There are no official indications.

Regulator-approved labeling and published study designs — never a recommendation.

Community-reported practice

Phase I doses. No community experiences; Phase I only.

Unverified self-reports. Not medical advice. Not endorsement.

Expected effects (community)

No community experiences; Phase I only.

Protocol — official vs community

Official / label

No official protocol exists — this compound has no approved product.

Community (anecdotal)

Structured protocol data for this entry is coming.

Human evidence

Human data are limited: small trials or case-series reports exist, without large randomized studies. Phase I completed; no further development.

Preclinical evidence

Phase I completed; no further development.

Known risks

  • Tolerated in Phase I.characterized
  • WADA prohibition (S1 anabolic agents)characterized

Teal: characterized in clinical/labeling contexts. Amber: theoretical or reported outside controlled settings.

Unknowns & evidence gaps

  • Long-term human safety
  • Optimal dose and pharmacokinetics

Frequently asked questions

References

Systematic references are being expanded; verify sources directly before any decision.