GH Pulse Stack (CJC + Ipa)

Muscle

Components

CJC-1295 no DAC / Mod GRF (1-29)Limited evidence IpamorelinLimited evidence

Rationale

Synergy of two mechanisms: a GHRH analogue (CJC/Mod GRF) increases GH pulse amplitude, while a ghrelin mimetic (Ipamorelin) releases GH via GHS-R. Together they give a more physiological pulsatile GH profile than either alone — the most popular "anti-aging/recomp" stack.

Evidence level

GHRH + GHRP synergy is documented in older clinical studies (up to ~2× higher GH peaks). Ipamorelin has human Phase I/II data; no long-term combination trials in humans exist.

Caution

Chronically elevated GH/IGF-1 — caution with diabetes, sleep apnea and cancer history. Water retention and hand numbness are common.